Opal Ventures
Opal Ventures is a thesis-driven venture capital firm focused on backing early-stage health tech startups in the US. They aim to transform the healthcare industry by investing in high-conviction, pre-seed stage companies. They prioritize building a strong relationship with their portfolio companies, fostering trust and transparency, and offering support beyond capital investment. The firm is operator-led, with the team offering expertise and hands-on assistance to founders. Opal Ventures focuses on being the first check into promising health tech startups. Their investment strategy involves providing a laser-focused approach on early-stage health tech, leveraging a broad network of advisors to support founders from the earliest stages of building. They offer operational support to their portfolio companies. Their stated goal is to build an open and trusting relationship with founders, making them the first point of contact when support is needed. The firm's commitment lies in providing early-stage capital and support to health tech startups that can transform healthcare in the US. They look for opportunities to be the first investor in these companies. The team comprises experienced operators who provide honest feedback and celebrate the successes of their founders. They support founders in accelerating their journey toward success. Opal Ventures' approach to value addition is to combine their investment with operational experience and network. This enables them to offer focused support to their founders during the critical early stages of company building. They differentiate themselves by building strong founder relationships based on trust and transparency.
Openseed
OpenseedVC focuses on investing first checks into experienced operators building companies at day zero, often before institutional capital shows up. The firm believes that early-stage failure is often related to team vision and execution under uncertainty, rather than just the idea itself. They aim to be the partner who leads with conviction on day zero, providing support even before traditional VCs arrive. OpenseedVC aims to invest in the next generation of world-changing technology solutions, built by exceptional operators who have the grit to navigate uncertainty in complex, emerging market environments. Maria Rotilu, Founder & General Partner, brings a background of scaling products and teams at Uber and Branch in complex, emerging market environments and also led the Oxford Seed Fund and co-led Octopus Ventures’ £10m First Cheque Fund for Europe. This experience has shaped her conviction that early-stage failure is often not about the idea; it is about team vision and execution under uncertainty. Openseed invests in outlier tech operators with unusually fast execution speed, obsessed domain experts with a bias for action, and serial founders with a track record of starting and scaling startups and innovations. The fund emphasizes providing conviction and support during the fragile early stages of execution, when even small, "day zero" decisions can compound into either massive scale or structural failure. OpenseedVC's operator network provides support from seasoned operators across Software Engineering, Product, People, and Go-To-Market.
OpenseedVC
Openseed VC invests in exceptional operators who are starting their own companies, providing up to $150k in seed funding and leveraging a global operator network for support from zero to one. Focuses on reinventing enterprise-scale rails for modern businesses, health innovations, and work productivity.
Orbimed Advisors
OrbiMed is a global investment firm focused on the healthcare industry. They aim to invest in world-class healthcare companies to drive innovation, address unmet medical needs, and improve patient outcomes. They focus on long-term growth trends led by global demographics and scientific innovation in treating disease. OrbiMed believes the healthcare industry's powerful growth profile, coupled with its magnitude and complexity, creates numerous investment opportunities. Their investment strategy is broad and flexible, covering the global healthcare industry from seed-stage venture capital to large publicly-traded companies. They invest through public equity, private equity, and private credit/royalty strategies. In private equity, OrbiMed often acts as a lead investor, actively helping portfolio companies to become market leaders, with a global investment scope including North America, Asia, and Europe. They also offer non-dilutive structured debt capital and royalty monetization solutions to commercial-stage healthcare companies and intellectual property owners. OrbiMed invests in companies engaged in the discovery and development of biopharmaceutical products, medical technologies, medical devices, diagnostics, drug discovery tools, and healthcare information technology and services. They seek companies focused on responsible, sustainable growth to build long-term shareholder value. They have been investing globally for over 25 years and currently manage approximately $20 billion across public and private company investments worldwide.
Owl Ventures
Owl Ventures is a global venture capital firm focused on investing in transformative learning and workforce AI companies across all stages and sectors. The firm believes education is the most powerful driver of human potential and aims to scale the world's most impactful education companies. They have a decade-long focus on EdTech and aim to not just invest but to build the market, scaling companies from pre-revenue to nine-figure businesses and coordinating M&A across their portfolio. Owl Ventures also prioritizes investments that create lasting change by expanding opportunity, driving equity, and advancing lifelong learning. The firm operates as a full-lifecycle partner, leading rounds from pre-seed through IPO and actively engaging throughout the growth cycle. They leverage their global LP network to gain access to global growth opportunities in education, workforce, and AI-driven learning, with investments spanning six continents. Their extensive portfolio of over 100 companies creates powerful synergies in distribution, talent, M&A, and insights, resulting in a network effect that benefits their portfolio companies. Owl Ventures is focused on backing bold ideas in education and work globally. They invest in companies at every stage, from pre-seed to pre-IPO, to help scale companies from their first customers to becoming global category leaders. Their portfolio spans the full learning journey, from PreK-12 and higher education to workforce development and lifelong learning, with a particular emphasis on AI-powered solutions that are reshaping how knowledge is created, shared, and scaled.
Oxford Capital
Oxford Capital is a venture capital firm based in Oxford, UK, that invests in early-stage and growth-stage companies across the UK. They focus on backing founders of innovative companies with disruptive potential, investing from pre-seed to growth and beyond. With over 25 years of experience, they have invested over £500m into over 100 companies. The firm provides individuals, families, and institutions the ability to participate in these investment opportunities. Oxford Capital aims to bridge the gap between entrepreneurs and private capital investors. The firm's strategy involves supporting companies from their earliest stages to later growth, enabling entrepreneurial successes. They are particularly interested in companies leveraging technology and science to solve complex problems. The firm's investment approach emphasizes backing companies that are creating new markets or disrupting existing ones. Oxford Capital looks for founders with a clear vision, strong execution capabilities, and the potential to build large, scalable businesses. They also focus on providing value beyond capital, offering support in areas such as strategy, operations, and fundraising. Oxford Capital actively monitors the venture capital landscape, providing commentary on industry trends and investment policy through its news and views section. They support the Enterprise Investment Scheme (EIS) as a means to encourage investment in early-stage companies. The firm has a strong emphasis on governance and sustainability in both mature and high-growth companies.
Oxford Technology
Oxford Technology specializes in investing in startup and early-stage technology companies based in and around Oxford, UK. Their investment strategy centers around leveraging SEIS and EIS tax reliefs to provide seed and follow-on funding to innovative tech ventures. They manage two funds: a flagship three-year combined SEIS and EIS fund and a Knowledge-Intensive EIS fund, each with slightly different risk/return profiles. The SEIS fund targets earlier-stage companies, investing a portion of the capital upfront and following on with high performers in subsequent years. The Knowledge-Intensive EIS fund focuses on companies already in their portfolio, offering a potentially lower risk/return profile. The firm typically invests up to £150k of seed funding into SEIS-eligible companies and up to £300k of EIS follow-on funding. They emphasize the importance of follow-on investments for achieving the best returns and exit multiples. Oxford Technology also runs WOTAN (Wider Oxford Technology Angel Network) to provide further investment opportunities. The firm prioritizes investments in companies with novel science or technology that can disrupt existing sectors or create new ones. They seek companies that are SEIS-eligible, especially those located in or around Oxford. Oxford Technology's investment approach includes tax relief benefits for investors under SEIS and EIS schemes. They provide investors with opportunities to participate in monthly presentations of follow-on EIS-eligible pitches. They also actively assist portfolio companies in their early years, especially those located near Oxford. Their investment philosophy is oriented towards providing both capital growth and tax reliefs.
Oxford Technology Management
Oxford Technology Management specializes in investing in startup and early-stage technology companies based in and around Oxford since 1983. The firm leverages the UK's SEIS (Seed Enterprise Investment Scheme) and EIS (Enterprise Investment Scheme) tax reliefs to provide investors with tax-efficient access to innovative technology startups. Their investment strategy focuses on providing seed funding to SEIS-eligible companies and follow-on EIS funding to high-performing ventures within their portfolio. The firm believes that the ability to make follow-on investments is crucial for achieving the best returns and highest exit multiples. Oxford Technology manages two funds: a flagship three-year combined SEIS and EIS fund, and an approved Knowledge-Intensive EIS fund. The SEIS and EIS Start-Up Fund invests in approximately eight tech startups over three tax years, allocating a third of the subscription to SEIS companies in the first year and providing follow-on EIS funding in subsequent years. The Knowledge-Intensive EIS Fund invests in five select EIS companies already within the Oxford Technology portfolio, offering a slightly lower risk/return profile due to the companies' progression and higher valuations. The firm emphasizes the benefits of capital growth and tax reliefs associated with SEIS and EIS investments, including income tax reduction, capital gains relief, and tax-free capital gains after three years. Oxford Technology aims to provide investors with opportunities for significant capital growth while mitigating risk through tax advantages and downside protection offered by the schemes. Oxford Technology also operates WOTAN – Wider Oxford Technology Angel Network, connecting investors with early-stage technology opportunities. They host monthly investor presentations featuring follow-on EIS-eligible pitches, further facilitating investment in promising startups.
Panache Ventures
Panache Ventures is Canada’s leading pre-seed & seed fund, dedicated to backing visionary founders from day one. They aim to be the first institutional investor on the cap table, providing initial investments up to $1.5M from their $100M Fund II. Panache focuses on supporting technology founders across all sectors nationwide, with hands-on support from operators-turned-investors. They emphasize a no-ego approach, focusing on practical assistance rather than board seats. The firm's strategy revolves around identifying and investing in founders with conviction and courage, providing them with the resources and support needed to scale their companies. Panache offers more than just capital, delivering operator-led support, leveraging a network of over 100 founders who have grown with their assistance. They do not emphasize board seats but a hands-on approach to mentorship and support. Panache emphasizes a national presence, implying a focus on the Canadian market and a commitment to supporting founders across the country. They highlight their experience as former operators, suggesting a practical, hands-on approach to helping their portfolio companies overcome challenges and achieve growth. The absence of ego suggests a collaborative and founder-centric approach, prioritizing the needs of the entrepreneurs they back.
Park Rangers Capital
Park Rangers Capital is a pre-seed and seed firm that focuses on backing founders with a built-in distribution edge. Their investment philosophy is rooted in the belief that software has become a commodity and that the loneliness epidemic in the U.S. is a significant problem. They believe the strongest companies of the next decade will address both by building communities, where users belong and are deeply connected to the brand. They seek founders who are building movements early on, with companies whose members are obsessive, loyal, and deeply connected to the brand, referring to these founders as 'elephants, not unicorns.' The firm's focus extends beyond mere product creation, emphasizing the importance of community building. They aim to support founders in turning customers into members and companies into movements, recognizing that distribution, community, and authenticity are key moats in today's market. They provide support in three core areas: content & storytelling, community access, and distribution strategy. Park Rangers Capital emphasizes the use of content to distribute ideas, build trust, and connect with founders. They are a solo GP shop supported by a Chief of Staff, venture partner, fractional writer, and a network of operators. Erica Wenger, the solo GP, has experience as a serial entrepreneur and early operator.
Plug & Play EMEA Ventures GmbH
Investing in seed-stage European startups, especially in Spain, across AI, fintech, sustainability, and mobility, by combining capital with Plug and Play's global acceleration and corporate networks.
Point Nine Capital (P9)
Point Nine invests in AI-driven startups across SaaS, B2B software, and emerging sectors like healthcare, robotics, and agriculture, focusing on pre-seed and seed-stage companies with global potential. The firm emphasizes thesis-driven investments, working closely with founders to accelerate growth and provide operational support.
Portage
Portage is a global investment platform focused on fintech and financial services. Their mission is to empower entrepreneurs reshaping financial services by providing flexible capital and a global network of investors, commercial partners, advisors, and value creation experts. They have deep industry knowledge and entrepreneurial experience, and are committed to supporting leaders in the fintech and financial services space. Portage leverages a thesis-driven investment approach, enabling differentiated insights, understanding of market dynamics and opportunities, and deep research and expertise. They aim to be long-term partners, with various pools of capital that allow them to partner with companies across all stages, from seed to later-stage. Their Value Creation team of vertical domain experts accelerates the growth of their portfolio companies through access to expertise in go-to-market, technology and cybersecurity, commercial partnerships, and business acceleration & M&A. Portage was founded in 2016 by Adam Felesky and Paul Desmarais III to help fintech and financial services entrepreneurs navigate the challenges of scaling from local startups to global companies. They started with early-stage fintech venture capital and have since expanded to late-stage fintech and financial services through Portage Capital Solutions in 2022. They have over 115 portfolio companies in 13 countries and have facilitated 142+ partnerships for their portfolio companies. Additionally, they have 1,000+ relationships with financial institutions and investors worldwide, with over 40 institutional, corporate, and family office investors, along with 20+ advisors with deep entrepreneurial and financial services experience.
Positron Ventures
Positron Ventures focuses on helping and funding Europe-based scientist-entrepreneurs who are pursuing moonshots for planetary health. They invest in scientist-entrepreneurs working on breakthroughs across the natural sciences, backing teams from day one in their pursuit of solving major global challenges. The firm often acts as the first believer and investor, offering support across all aspects of building a company. They proactively conduct deep dives in scientific niches to thoroughly understand the state of science in a given field before investing. Their investment strategy appears to be focused on early-stage, pre-seed deeptech companies. Positron Ventures aims to turn breakthrough research into successful companies by investing at the frontier of science and building systems that help deeptech founders succeed. This includes support across operations, people, communications, and LP engagement. Positron Ventures invests in deeptech funds in Europe and the US, and is launching the Positron Foundation to support high-risk, pre-commercial research.
PreSeed Ventures (PSV)
PreSeed Ventures (PSV) is a venture house dedicated to clearing the path for founders building impactful companies. They operate through a hybrid setup, comprising PSV Foundry, PSV Lab, and two distinct venture funds: PSV Tech and PSV Hafnium. This structure allows PSV to rethink existing models and maximize their impact beyond individual investments. They aim to punch above their weight and build a more conscious future. PSV Foundry focuses on closing gaps in the startup ecosystem, while PSV Tech is dedicated to backing founders pre-product/market fit. PSV Hafnium takes early bets on scientists, engineers, and entrepreneurs in deep tech. PSV Lab sometimes takes part in creating the future themselves through internal projects. PSV emphasizes a commitment to ESG and impact, as evidenced by their Head of ESG & Impact's participation in discussions on climate solutions and the sustainability-related disclosures for PSV Hafnium and PSV Tech funds. This indicates a focus on investing in companies that not only achieve financial success but also contribute positively to society and the environment. Ultimately, PSV aims to support ambitious founders from the earliest stages, particularly in the Nordics, by providing capital, guidance, and resources to help them scale their businesses and drive innovation.
Primary Venture Partners
Primary Venture Partners focuses on backing founders building innovative companies that haven't yet been proven, investing at the seed stage. They aim to support founders in turning seemingly impossible ideas into successful companies. Their investment theses appear to be specialized, with partners focusing on areas like GTM Tech, AI-native consumer products, enterprise software, supply chain, industrial tech, fintech, and cybersecurity. Their approach combines deep sector specialization with a 60+ person operating team to deliver hands-on support to their portfolio companies. Brad Svrluga's investment thesis centers around identifying founders using AI to improve complex operational systems, converting judgment and execution into software advantages. Ben Sun focuses on the consumer platform shift, backing AI-native products that become trusted partners for consumers. Cassie Young's 2026 investment thesis focuses on GTM Tech.
Primo Ventures
Primo Ventures is an Italian independent investment platform focusing on key technological sectors vital for economic development. They operate across four main sectors: Digital, Space Economy, Climate Tech, and Healthcare. The firm invests in companies that demonstrate potential for significant impact and growth within these sectors. Primo Ventures aims to support and scale innovative technologies by providing capital and resources to promising startups. By focusing on these critical areas, Primo Ventures seeks to drive innovation and contribute to economic advancement through strategic investments and active involvement with its portfolio companies. Their portfolio companies demonstrate the firm's commitment to supporting impactful innovations. They aim to foster growth and facilitate the scaling of technologies that address critical needs and contribute to societal advancement. They seek to provide not only financial backing but also strategic guidance and operational support to their portfolio companies, enabling them to achieve their full potential and drive significant impact in their respective industries. By focusing on these key technological sectors, Primo Ventures aims to create a diversified portfolio of companies poised for growth and success. The firm's investment strategy is rooted in identifying and supporting innovative companies that can create value and contribute to economic development. Their targeted investment approach, combined with their network and expertise, allows them to play a significant role in fostering innovation and driving growth in the Italian and European tech ecosystems.
ProVenture
ProVenture is a seed and early-stage venture capital firm focused on digital technology startups. They aim to partner with ambitious founders to transform bold ideas into valuable realities. With three funds under management, they offer not only financial support but also hands-on guidance and experience to navigate the complexities of growth. They prioritize building lasting value for entrepreneurs by leveraging their own entrepreneurial backgrounds. They work closely with founders from initial stages through exit, aiming for impactful results for both the companies and their investors. ProVenture's mission is to empower exceptional entrepreneurs in building transformative tech companies while delivering significant returns for their investors. Their team, based in Trondheim and Stavanger, combines practical entrepreneurial experience with strategic insights. They emphasize a partnership approach, leveraging their experience in scaling and exiting global tech companies to guide founders through every phase of their journey. Their history shows a track record of successful exits and IPOs, demonstrating their ability to help companies achieve significant milestones. Their investment approach is centered around identifying and supporting startups that are solving real-world problems using digital technologies. They look beyond just funding, offering a trusted partnership built on expertise and a focus on long-term success. They aim to deliver meaningful results for their founders' visions and the shared goals of their investors.
ProVenture Management
ProVenture Management is a seed and early-stage venture capital firm based in Norway, focusing on digital technology startups. Their investment thesis revolves around partnering with ambitious founders who are solving real-world problems with innovative digital solutions. They provide not only funding but also hands-on guidance and expertise, leveraging their experience in building, scaling, and exiting global tech companies. They aim to be a trusted partner, offering strategic insight and support throughout the startup journey, from initial stages to exit. Their mission is to empower exceptional entrepreneurs to build transformative tech companies while delivering meaningful returns for their investors. ProVenture's strategy emphasizes active involvement with their portfolio companies. They work alongside founders to achieve meaningful results for both the company's vision and their investors' goals. With a track record of over 50 exits and 3 IPOs, the team brings valuable expertise to guide founders through every stage of growth. They operate from offices in Trondheim and Stavanger, combining entrepreneurial experience with strategic insight to support their investments. The firm manages three funds with a total of 1.3 billion NOK in assets under management. Their approach is rooted in a deep understanding of the complexities of scaling tech companies. This understanding allows them to provide tailored support that goes beyond mere capital injection, creating lasting value for both entrepreneurs and investors. They aim to foster long-term success through close collaboration and strategic partnership. ProVenture's investment approach appears to be stage agnostic within the seed and early-stage scope, providing support from "first steps to exit". Their team's diverse backgrounds, including experience at McKinsey & Company, Investinor, and as serial entrepreneurs, bring a wide range of skills to their investment activities. This breadth of experience enables them to provide effective guidance and support to their portfolio companies across various aspects of business development and scaling.
Project A Studio
Project A Studio is a proving ground for Europe's boldest entrepreneurial talent, partnering with founders at the ideation and validation stage. They provide hands-on support from their experienced team, helping to shape and test the founder's vision. When conviction is mutual, they lead the pre-seed round on founder-fair terms and bring in high-signal angels.
QBIC III Fund
Qbic is an inter-university venture capital fund that invests in the transformation of technological breakthroughs into sustainable businesses. They focus on supporting spin-offs from universities and research institutions, aiming to bridge the gap between academic innovation and commercial success. Their strategy involves providing early-stage funding and support to companies operating in sectors where scientific advancements can drive significant market impact.
REDangels
REDangels is a business angel network that provides initial funding and support to entrepreneurs to create attractive startups and prepare them for further investments. They focus on the seed and pre-seed stages, helping startups validate their ideas and accelerate their growth. They leverage their experience, know-how, and network to assist startups in building an attractive business, finding subsequent investors, and negotiating future deals. The firm emphasizes the importance of having a relevant market opportunity, a strong entrepreneurial team, and a well-defined strategy. Their investment process involves screening applications, meeting with selected startups, negotiating deal terms, pitching at the investment committee, and ultimately realizing the investment.
RLC Ventures
Concept Ventures focuses on providing tailored support to founders based on their experience level, rather than adhering to strict sector or vertical focuses. They emphasize the importance of the founder-VC relationship and aim to be the right fit for the founders they back. They invest in first rounds, with an emphasis on being early stage investors. The firm's team has operational know-how to guide companies to Series A and beyond.
Realyze Ventures
Realyze Ventures invests in European startups leveraging technology and innovation to decarbonize the built environment, improve process efficiency, and enable superior returns. Focus areas include sustainability, energy efficiency, digitalization, and scalable solutions for real estate and construction challenges.